Biochemical Studies of Vitamin E and Selenium Deficiency in Growing Piglets

Regional Institute of Veterinary Medicine, BG-4000 Plovdiv, Bulgaria


HRISTEV, H., L. BELCHEV and A. ANGELOV, 2001. Biochemical studies of vitamin E and selenium deficiency in growing piglets. Bulg. J. Agric. Sci., 7: 527-531

The changes of vitamin E and selenium, lactatedehydrogenase, creatine, peroxide resistance to erythrocyte lipids, glutamatedehydrogenase, aspartate aminotransaminase, alanine aminotransaminase, potassium and sodium were investigated in growing piglets with vitamin E and selenium deficiency, depending on lipid quality and vitamin E levels in the feed.
It was established that feed lipids have a high oxidation rate (within 20.2 – 88 meq/kg), i.e. 6.5 to 29.5 times above the average adopted value and insignificant vitamin E concentration (0.3 – 65.5 mg%) or none.
The dynamics of biochemical processes is influenced by lipid quality and the concentration of vitamin E and selenium in feed. Thus the activity of aminotransaminases ASAT and ALAT, hydrogenases LDH and GDH, creatinine (C) and peroxide resistance of erythrocyte lipids (PREL) increases in ill piglets, while the levels of extracellular electrolyte Na and intracellular electrolyte K remain stable.
The biochemical changes observed in piglets with vitamin E and selenium deficiency are indicative of the participation of oxidation stress in disease pathology.

Key words: vitamin E, Se deficiency, oxidation stability of feed lipids, electrolytes, creatine, ASAT, ALAT, GDH